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From: Char on 11 Jul 2010 09:29
On 7/10/2010 6:19 PM, cshenk wrote:
> Char is good people but has a belief that such products are more harmful
> than beneficial.
And it's based on factual evidence, not belief.
> One good thing about the super hot summer so far is it seems to have
> killed the yard fleas down better. Less need to use yard products (we
> use an organic soap which is environment friendly and kid/people/pet safe).
Nematodes are great for outside. They eat fleas.
> I'm not familiar with revolution but frontline is supposed to be good.
> The ones I used to get via my vet are now over the counter here in the
Frontline is fipronil.
Fipronil has been shown to mutate proteins and to kill human liver
cells at concentrations of 0.1 nM. Using fipronil's molecular weight
= 437.15 g/mol leads to 44ppt.
That is a ~very~ low exposure. Meanwhile, the government allows fipronil
residue in foods at levels 220x to 34,000x higher.
The researchers noticed that the dose-response curve was non-monotonic.
In other words, the smallest doses were more toxic than larger ones (see
hormesis for more about this kind of toxic behavior).
Also, the researchers found that fipronil sulfone, a chemical left over
after fipronil breaks down, was more toxic than fipronil itself.
Fipronil sulfone caused cell death at lower doses.
This study found that, one day after applying FrontLine to an adult
dog, petting it for just 5 minutes while wearing gloves resulted in
exposure of 600 ppm.
Typical owners handle their pets more than 5 minutes per day.
Also, any surface the pet contacts will become contaminated, thereby
increasing exposure. Dander will also remain toxic for a period.
Children and anyone suffering an excitoxin-related illness are at higher
risk. Veterinarians and other pet care providers also have increased risk.
Fipronil is highly toxic to bees, with death resulting from 0.1 ng
exposure. Bees are a critical link in the ecosystem. Fipronil (and
imidacloprid) are implicated in Colony Collapse Disorder.
It also causes Thyroid cancer (possible human carcinogen)
Increased organ weights, altered thyroid hormones
Loss of appetite, underactivity, convulsions, whining, barking, crying
(vocalization), body twitches/tremors, overactivity, salivation,
stiffened limbs,unsteady gait, incoordination, labored breathing
Reduced fertility, decreased litter size and body weights in litters,
fetus mortality, severe moist inflammation, ulcerations, skin sloughing,
chemical burn, itching, hair loss at and beyond the application site
> Around here, most fleas come in from outside. There are several yard
> things you can use to reduce the problems in addition to the flea meds.
> Diatomaceous earth does a number on them so you can add this to pet
> sleeping areas and near your entrance/exits to the house.
I use it on the carpets, sprinkling it on then brooming it in. Works great!
I use the
> organic soap spray in the back yard every 2 weeks (pesticidal types last
> up to 4 weeks but Cash doesnt take well to them).
This site contains hundreds of first-hand accounts about pets that
have suffered adverse reactions including death from pesticide
At least nine class-action lawsuits are pending against makers of
topical flea and tick products in the wake of a U.S. Environmental
Protection Agency (EPA) investigation into safety of the pesticides used
on dogs and cats.
One law firm in New Jersey has filed seven of the suits one each
against Merial Ltd., and its parent companies Merck & Co., Inc. and
Sanofi-Aventis U.S., Inc., maker of Frontline; Summit VetPharm LLC and
its parent company, Sumitomo Corp. of America, maker of Vectra; The
Hartz Mountain Corp. and its parent, Sumitomo, maker of UltraGuard;
Bayer Healthcare LLC, maker of Advantage and K9 Advantix; Sergeants Pet
Care Products, Inc., maker of SentryPro; Farnam Companies, Inc., maker
of Bio Spot and Adams; and Wellmark International, Inc., maker of Zodiac.